New research reveals that Alzheimer’s disease may impair nerve function not by reducing myelin, but by altering the proteins at the critical interface between axons and their myelin sheath. Scientists found structural abnormalities in the paranode region, where myelin attaches to axons, including clogged nutrient channels and protein buildup that could block signal transmission.
Alzheimer’s May Disrupt Nerve Insulation Without Reducing Myelin
