A new study identifies two proteins that interact with a mutant FUS variant linked to familial ALS, offering a potential therapeutic target. Researchers found that inhibiting these proteins in motor neurons derived from human stem cells reduced ALS-related changes. The findings suggest that similar mechanisms may be involved in sporadic ALS, which affects most patients. Further research will explore these proteins’ roles in other ALS-related genes and sporadic cases.
Two New Proteins Linked to ALS
