{"id":953,"date":"2025-06-28T19:13:11","date_gmt":"2025-06-28T19:13:11","guid":{"rendered":"http:\/\/sniffmybody.com\/?p=953"},"modified":"2025-07-02T11:27:26","modified_gmt":"2025-07-02T11:27:26","slug":"one-gene-rewires-fear-circuits-and-fuels-anxiety","status":"publish","type":"post","link":"http:\/\/sniffmybody.com\/index.php\/2025\/06\/28\/one-gene-rewires-fear-circuits-and-fuels-anxiety\/","title":{"rendered":"One Gene Rewires Fear Circuits and Fuels Anxiety"},"content":{"rendered":"<p><a href=\"https:\/\/neurosciencenews.com\/pten-anxiety-autism-29367\/\" title=\"One Gene Rewires Fear Circuits and Fuels Anxiety\" rel=\"nofollow\"><img loading=\"lazy\" width=\"1155\" height=\"770\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" class=\"webfeedsFeaturedVisual wp-post-image lazyload\" alt=\"This shows a Brain.\" style=\"float: left;margin-right: 5px\" data-src=\"http:\/\/sniffmybody.com\/wp-content\/uploads\/2025\/06\/PTEN-ASD-anxiety-neurosciecne-1155x770-1.jpg\"><\/a>Researchers have uncovered how losing the autism-linked gene PTEN in a specific set of inhibitory neurons reshapes brain circuits tied to fear and anxiety. Using advanced circuit-mapping techniques, they found that deleting PTEN in somatostatin-expressing neurons of the amygdala disrupted local inhibition by 50% while strengthening excitatory input from nearby brain regions. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have uncovered how losing the autism-linked gene PTEN in a specific set of inhibitory neurons reshapes brain circuits tied to fear and anxiety. Using advanced circuit-mapping techniques, they found that deleting PTEN in somatostatin-expressing neurons of the amygdala disrupted local inhibition by 50% while strengthening excitatory input from nearby brain regions.<\/p>\n","protected":false},"author":1,"featured_media":955,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[12],"tags":[],"_links":{"self":[{"href":"http:\/\/sniffmybody.com\/index.php\/wp-json\/wp\/v2\/posts\/953"}],"collection":[{"href":"http:\/\/sniffmybody.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/sniffmybody.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/sniffmybody.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/sniffmybody.com\/index.php\/wp-json\/wp\/v2\/comments?post=953"}],"version-history":[{"count":2,"href":"http:\/\/sniffmybody.com\/index.php\/wp-json\/wp\/v2\/posts\/953\/revisions"}],"predecessor-version":[{"id":956,"href":"http:\/\/sniffmybody.com\/index.php\/wp-json\/wp\/v2\/posts\/953\/revisions\/956"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/sniffmybody.com\/index.php\/wp-json\/wp\/v2\/media\/955"}],"wp:attachment":[{"href":"http:\/\/sniffmybody.com\/index.php\/wp-json\/wp\/v2\/media?parent=953"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/sniffmybody.com\/index.php\/wp-json\/wp\/v2\/categories?post=953"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/sniffmybody.com\/index.php\/wp-json\/wp\/v2\/tags?post=953"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}