Researchers have developed an innovative device that can diagnose glioblastoma, an aggressive brain cancer, in under an hour using a novel biochip. The chip leverages electrokinetic technology to detect active Epidermal Growth Factor Receptors (EGFRs) in extracellular vesicles from a small blood sample. This method offers high sensitivity and selectivity, minimizing interference and potentially improving […]
COVID’s Inflammation Linked to Long-Term Brain Effects
New research uncovers how COVID-19 may cause neuroinflammation, leading to persistent neurological symptoms even after recovery. The study found elevated levels of pro-inflammatory cytokines and significant changes in cerebrospinal fluid among hospitalized patients, highlighting the brain’s vulnerability to the virus.
Miniaturized Brain-Machine Interface Translates Thoughts Into Text
Researchers developed a compact, low-power brain-machine interface (BMI) called MiBMI, designed to enhance communication for individuals with severe motor impairments. The device translates neural activity into text with 91% accuracy, using a highly miniaturized system that processes data in real-time. This innovation opens the door to practical, implantable BMIs, promising significant improvements in quality of […]
Blocking a Brain Pathway Reverses Memory Loss in Alzheimer’s
Blocking the kynurenine pathway, a regulator of brain metabolism, can restore cognitive function in lab mice with Alzheimer’s disease. The pathway is overactivated in Alzheimer’s, disrupting glucose metabolism and starving neurons of energy. By inhibiting this pathway, researchers improved memory and brain plasticity in mice, offering hope for new treatments in humans. IDO1 inhibitors, currently […]
Does Multiple Sclerosis Lower Dementia Risk?
Research has revealed that individuals with multiple sclerosis (MS) are significantly less likely to exhibit the molecular signs of Alzheimer’s disease, suggesting a protective element in MS that could inspire new Alzheimer’s treatments. The study found that MS patients had 50% less amyloid plaque accumulation, a key indicator of Alzheimer’s, compared to non-MS individuals. This […]
Two New Proteins Linked to ALS
A new study identifies two proteins that interact with a mutant FUS variant linked to familial ALS, offering a potential therapeutic target. Researchers found that inhibiting these proteins in motor neurons derived from human stem cells reduced ALS-related changes. The findings suggest that similar mechanisms may be involved in sporadic ALS, which affects most patients. […]
COVID’s Spike Protein Enhances Ability to Infect Brain
Researchers have discovered a mutation in the SARS-CoV-2 spike protein that enhances its ability to infect the central nervous system, potentially explaining neurological symptoms and “long COVID.” The mutation was found to allow the virus to better infiltrate the brain, with implications for future treatments targeting COVID-19’s effects on the brain. The findings highlight the […]
Gene Defect Causes Abnormal Brain Size
Mutations in the gene ZNRF3 can lead to abnormal brain sizes—either too large or too small—causing various neurological symptoms. This gene, known for its role in cancer, is crucial in regulating brain cell production. The study found that specific mutations in the gene disrupt the balance of brain cell development, with potential implications for cancer […]
Music Therapy Helps in Brain Rehabilitation
Music-based movement therapy, the Ronnie Gardiner Method, shows promise in aiding rehabilitation for stroke and other brain disorders, according to a review from researchers. This rhythmic and engaging approach, which involves coordinated movements and sounds, has been well-received by participants for its enjoyable and social nature. While the method’s potential benefits for stroke recovery are […]
Molecule Discovery Could Revolutionize Chronic Pain Treatment
Researchers have identified a natural molecule, phosphatidic acid, that reduces the sensitivity of touch-sensing ion channels, providing a promising new avenue for managing chronic pain. By increasing levels of this molecule, cells become less sensitive to touch, which was confirmed through tests on sensory neurons and in mice. This discovery could lead to more targeted […]